BioData @ International Symposium on Respiratory Systems in Gram-positive Bacteria, Lunds, Sweeden, 11 April 2019
Ana Portugal Melo, BioData.pt's Executive Director participated today in the International Symposium on Respiratory Systems in Gram-positive Bacteria in Lunds, Sweeden, with the article "Respiratory supercomplexes of bacteria in perspective":
Microbial respiratory supercomplexes have a history of more than 30 years of passion and skepticism, encompassed by emerging technologies that progressively enable researchers to more detailed findings. We have travelled from membrane solubilization to cryo electron microscopy, and maybe one day to super resolution microscopy. Different sources and enormous amounts of data have contributed to the state of the art, like enzymology, spectroscopy and different omics among others. Lots of data have been produce, lots is being produced and more will be. Several questions are still to be answered: can these supramolecular structures be observed in vivo? How do they form? Which interactions are crucial for their stability and function? Are supercomplexes crucial for bacterial survival and if so good targets for drug design or designing super-growing bacteria to be used by industry? So many questions, so many achievements, so much data. Could a community driven RSC repository allow an integrated perspective of the knowledge in field, rediscover underestimated findings, allow better experiment design and set the pace for new endeavors? Can a community super focused in atomic details be open to a data management defy? BioData.pt is challenging!